Research Supporting Sublingual Immunotherapy

Research Supporting Sublingual Immunotherapy

Millions of people across the globe suffer from allergies, asthma, and other related immunologic disease.

Though clinical practice of sublingual immunotherapy in the U.S. dates

back nearly 100 years, sublingual immunotherapy research validating

what was learned clinically has only begun to garner attention in the past few decades.

A large number of controlled clinical trials in Europe have shown

the effectiveness of sublingual immunotherapy in the treatment

of allergic rhinitis and asthma for single antigens.

More studies are underway in the U.S. and globally,

including studies that explore food allergies.

Additional research has shed light on the mechanisms behind

sublingual immunotherapy, notably the unique role

dendritic cells under the tongue play in building allergen tolerance.